Gene Therapy

How will gene therapy survive its success? (Kaemmerer W)

Bioengineering & Translation Med 2018

Interesting discussion of the author's hypothesis of the "hype cycle" surrounding gene therapy, and gives an overview of the major past and current hurdles facing gene therapy commercialization.

Gene therapy clinical trials worldwide to 2017: An update (Ginn S et al)

Journal of Gene Medicine 2018

Some numbers on gene therapy clinical development.

Advancing Gene Therapies And Curative Health Care Through Value-Based Payment Reform (Daniel G, Leschly N, Marrazzo J & McClellan M)

Health Affairs Blog 2017

Authored by blubird bio and Spark Therapeutics' CEO, this blog discusses various value-based reimbursement strategies and their potential use for gene therapies.

Gene therapy: evidence, value and affordability in the US health care system (Hampson G et al)

J. Comparative Effectiveness Research 2017

Meeting report, discusses three broad challenges facing gene therapies (evidence of efficacy, assessing value, and affordability) and suggests potential solutions as informed by KOL discussions.

GENE THERAPY: Understanding the Science, Assessing the Evidence, and Paying for Value (ICER)

ICER Report 2017

Gene therapy’s out-of-body experience (Scott C & DeFrancesco L)

Nature Biotechnology 2016

The special case of gene therapy pricing (Brennan, T. & Wilson, J.)

Nature Biotech 2014